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1

Blame it on the metabolite: 3,5-dichloraniline rather than the parent compound is responsible for decreasing diversity and function of soil microorganisms

Vasileiadis, S., Puglisi, E., Papadopoulou, E. S., Pertile, G., Suciu, N., Pappolla, R. A., Tourna, M., Karas, P. A., Papadimitriou, F., Kasiotakis, A., Ipsilanti, N., Ferrarini, A., Sułowicz, S., For

Journal:

Applied and Environmental Microbiology

Year:

2018

Language:

english

File:

PDF, 770 KB

english, 2018

2

Brain magnetic resonance imaging features in multiple sclerosis and neuromyelitis optica spectrum disorders patients with or without aquaporin-4 antibody in a Latin American population

Silveira, Facundo, Pappolla, AgustÃn, SÃ¡nchez, Francisco, Marques, Vanessa Daccach, de Castillo, Ibis Soto, Tkachuk, VerÃ³nica, Caride, Alejandro, Castillo, Maria C., Cristiano, Edgardo, Cruz, Camil

Journal:

Multiple Sclerosis and Related Disorders

Year:

2020

Language:

english

File:

PDF, 601 KB

english, 2020

3

Is insulin resistance the cause of fibromyalgia? A preliminary report

Pappolla, Miguel A., Manchikanti, Laxmaiah, Andersen, Clark R., Greig, Nigel H., Ahmed, Fawad, Fang, Xiang, Seffinger, Michael A., Trescot, Andrea M., Holscher, Christian

Journal:

Year:

2019

File:

PDF, 634 KB

2019

4

Multiple sclerosis and neuromyelitis optica spectrum disorders in Argentina: comparing baseline data from the Argentinean MS Registry (RelevarEM)

Rojas, Juan Ignacio, Serena, Marina Alonso, Garcea, Orlando, Patrucco, Liliana, Carrá, Adriana, Correale, Jorge, Vrech, Carlos, Pappolla, Agustín, Miguez, Jimena, Doldan, María L., Silveira, Facundo,

Journal:

Neurological Sciences

Year:

2020

Language:

english

File:

PDF, 305 KB

english, 2020

5

Bradykinin induces superoxide anion release from human endothelial cells

James A. Holland, Kirkwood A. Pritchard, Miguel A. Pappolla, Michael S. Wolin, Nancy J. Rogers, Michael B. Stemerman

Journal:

Journal of Cellular Physiology

Year:

1990

Language:

english

File:

PDF, 541 KB

english, 1990

6

Evidence for intracellular cleavage of the Alzheimer's amyloid precursor in PC12 cells

K. Sambamurti, J. Shioi, J. P. Anderson, M. A. Pappolla, Dr. N. K. Robakis

Journal:

Journal of Neuroscience Research

Year:

1992

Language:

english

File:

PDF, 1.07 MB

english, 1992

7

Evidence that secretase cleavage of cell surface Alzheimer amyloid precursor occurs after normal endocytic internalization

Dr. L. M. Refolo, K. Sambamurti, S. Efthimiopoulos, M. A. Pappolla, N. K. Robakis

Journal:

Journal of Neuroscience Research

Year:

1995

Language:

english

File:

PDF, 2.25 MB

english, 1995

8

Detection of Alzheimer's amyloid in transgenic mice using magnetic resonance microimaging

Youssef Zaim Wadghiri, Einar M. Sigurdsson, Marcin Sadowski, James I. Elliott, Yongsheng Li, Henrieta Scholtzova, Cheuk Ying Tang, Gilbert Aguinaldo, Miguel Pappolla, Karen Duff, Thomas Wisniewski, Da

Journal:

Magnetic Resonance in Medicine

Year:

2003

Language:

english

File:

PDF, 658 KB

english, 2003

9

The neuroprotective activities of melatonin against the Alzheimer β-protein are not mediated by melatonin membrane receptors

Miguel A. Pappolla, Marcia J. Simovich, Tara Bryant-Thomas, Yau-Jan Chyan, Burkhard Poeggeler, Margarita Dubocovich, Roger Bick, George Perry, Felix Cruz-Sanchez, Mark A. Smith

Journal:

Journal of Pineal Research

Year:

2002

Language:

english

File:

PDF, 566 KB

english, 2002

10

Amyloid-β Deposition in Alzheimer Transgenic Mice Is Associated with Oxidative Stress

Mark A. Smith, Keisuke Hirai, Karen Hsiao, Miguel A. Pappolla, Peggy L. R. Harris, Sandra L. Siedlak, Massimo Tabaton, George Perry

Journal:

Journal of Neurochemistry

Year:

1998

Language:

english

File:

PDF, 606 KB

english, 1998

11

Induction of NADPH cytochrome P450 reductase by the Alzheimer β-protein. Amyloid as a ‘foreign body’

Miguel A. Pappolla, Rawhi A. Omar, Yau-Jan Chyan, Jorge Ghiso, Karen Hsiao, Peter Bozner, George Perry, Mark A. Smith, Felix Cruz-Sanchez

Journal:

Journal of Neurochemistry

Year:

2001

Language:

english

File:

PDF, 562 KB

english, 2001

12

Serum protein leakage in aged human brain and inhibition of ligand binding at alpha2- adrenergic and cholinergic binding sites

Miguel A. Pappolla, Anne C. Andorn

Journal:

Year:

1987

Language:

english

File:

PDF, 2.89 MB

english, 1987

13

Ultrastructural evidence that insoluble microtubules are components of the neurofibrillary tangle

Miguel A. Pappolla, Julia Alzofon, James McMahon, Theodor J. Theodoropoulos

Journal:

European Archives of Psychiatry and Clinical Neuroscience

Year:

1990

Language:

english

File:

PDF, 1.45 MB

english, 1990

14

Oxygen free radicals as inducers of heat shock protein synthesis in cultured human neuroblastoma cells: Relevance to neurodegenerative disease

Rawhi Omar, Miguel Pappolla

Journal:

European Archives of Psychiatry and Clinical Neuroscience

Year:

1993

Language:

english

File:

PDF, 986 KB

english, 1993

15

The heat shock/oxidative stress connection

M. A. Pappolla, M. Sos, R. A. Omar, K. Sambamurti

Journal:

Journal of Molecular Neuroscience

Year:

2006

Language:

english

File:

PDF, 1.74 MB

english, 2006

16

Systemic complement depletion reduces inflammation and demyelination in adoptive transfer experimental allergic neuritis

F. J. Vriesendorp, Robyn E. Flynn, Michael R. Malone, Miguel A. Pappolla

Journal:

Acta Neuropathologica

Year:

1998

Language:

english

File:

PDF, 289 KB

english, 1998

17

An assessment of the antioxidant and the antiamyloidogenic properties of melatonin: implications for Alzheimer's disease

M. A. Pappolla, Y. -J. Chyan, B. Poeggeler, B. Frangione, G. Wilson, J. Ghiso, R. J. Reiter

Journal:

Journal of Neural Transmission

Year:

2000

Language:

english

File:

PDF, 1.51 MB

english, 2000

18

Alzheimer’s Disease—A Dysfunction in Cholesterol and Lipid Metabolism

Walter J. Lukiw, Miguel Pappolla, Ricardo Palacios Pelaez, Nicolas G. Bazan

Journal:

Cellular and Molecular Neurobiology

Year:

2005

Language:

english

File:

PDF, 82 KB

english, 2005

19

Insulysin Cleaves the APP Cytoplasmic Fragment at Multiple Sites

Chitra Venugopal, Miguel A. Pappolla, Kumar Sambamurti

Journal:

Neurochemical Research

Year:

2007

Language:

english

File:

PDF, 393 KB

english, 2007

20

Statin therapy for Alzheimer’s disease

Suzana S. Petanceska, Steven DeRosa, Vicki Olm, Nichole Diaz, Ali Sharma, Tara Thomas-Bryant, Karen Duff, Miguel Pappolla, Lorenzo M. Refolo

Journal:

Journal of Molecular Neuroscience

Year:

2002

Language:

english

File:

PDF, 103 KB

english, 2002

21

Development of indole-3-propionic acid (OXIGON™) for alzheimer’s disease

Paul E. Bendheim, Burkhard Poeggeler, Eyal Neria, Vivi Ziv, Miguel A. Pappolla, Daniel G. Chain

Journal:

Journal of Molecular Neuroscience

Year:

2002

Language:

english

File:

PDF, 84 KB

english, 2002

22

A unique case of limb-girdle muscular dystrophy type 2A carrying novel compound heterozygous mutations in the human CAPN3 gene

E. Matsubara, A. Tsuchiya, N. Minami, I. Nishino, M. A. Pappolla, M. Shoji, K. Abe

Journal:

European Journal of Neurology

Year:

2007

Language:

english

File:

PDF, 1.13 MB

english, 2007

23

Mitochondrial medicine: neuroprotection and life extension by the new amphiphilic nitrone LPBNAH acting as a highly potent antioxidant agent

Burkhard Poeggeler, Grégory Durand, Ange Polidori, Miguel A. Pappolla, Ignacio Vega-Naredo, Ana Coto-Montes, Jutta Böker, Rüdiger Hardeland, Bernard Pucci

Journal:

Journal of Neurochemistry

Year:

2005

Language:

english

File:

PDF, 210 KB

english, 2005

24

Targets for AD treatment: conflicting messages from γ-secretase inhibitors

Kumar Sambamurti, Nigel H. Greig, Tadanobu Utsuki, Eliza L. Barnwell, Ekta Sharma, Cheryl Mazell, Narayan R. Bhat, Mark S. Kindy, Debomoy K. Lahiri, Miguel A. Pappolla

Journal:

Journal of Neurochemistry

Year:

2011

Language:

english

File:

PDF, 594 KB

english, 2011

25

Leptin and the skin: a new frontier

Burkhard Poeggeler, Carla Schulz, Miguel A. Pappolla, Enikő Bodó, Stephan Tiede, Hendrik Lehnert, Ralf Paus

Journal:

Experimental Dermatology

Year:

2010

Language:

english

File:

PDF, 462 KB

english, 2010

26

Alzheimer β protein mediated oxidative damage of mitochondrial DNA: Prevention by melatonin

M. A. Pappolla, Y.-J. Chyan, B. Poeggeler, P. Bozner, J. Ghiso, S. P. LeDoux, G. L. Wilson

Journal:

Journal of Pineal Research

Year:

1999

Language:

english

File:

PDF, 447 KB

english, 1999

27

Prophylactic Actions of Melatonin in Oxidative Neurotoxicity

RUSSEL J. REITER, JUAN M. GUERRERO, GERMAINE ESCAMES, MIGUEL A. PAPPOLLA, DARIO ACUÑA-CASTROVIEJO

Journal:

Annals of the New York Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 604 KB

english, 1997

28

Melatonin Relieves the Neural Oxidative Burden that Contributes to Dementias

RUSSEL J. REITER, DUN-XIAN TAN, MIGUEL A. PAPPOLLA

Journal:

Annals of the New York Academy of Sciences

Year:

2004

Language:

english

File:

PDF, 255 KB

english, 2004

29

β-secretase processing of the Alzheimer’s amyloid protein precursor (APP)

Laura Marlow, Melissa Cain, Miguel A. Pappolla, Kumar Sambamurti

Journal:

Journal of Molecular Neuroscience

Year:

2003

Language:

english

File:

PDF, 760 KB

english, 2003

30

Changes in apolipoprotein E expression in response to dietary and pharmacological modulation of cholesterol

Suzana S. Petanceska, Steven DeRosa, Ali Sharma, Nichole Diaz, Karen Duff, Steven G. Tint, Lorenzo M. Refolo, Miguel Pappolla

Journal:

Journal of Molecular Neuroscience

Year:

2003

Language:

english

File:

PDF, 450 KB

english, 2003

31

Reinduction of Experimental Autoimmune Encephalomyelitis in Mice

J.William Lindsey, Miguel Pappolla, Lawrence Steinman

Journal:

Cellular Immunology

Year:

1995

File:

PDF, 365 KB

1995

32

Aging of the neuroendocrine system: Impaired neuropeptide control of thyroid stimulating hormone

Theodor J. Theodoropolous, Miguel A. Pappolla

Journal:

Year:

1990

Language:

english

File:

PDF, 180 KB

english, 1990

33

Hyperhomocysteinemic Alzheimer's mouse model of amyloidosis shows increased brain amyloid β peptide levels

Javier Pacheco-Quinto, Elena B. Rodriguez de Turco, Steven DeRosa, Altovise Howard, Felix Cruz-Sanchez, Kumar Sambamurti, Lorenzo Refolo, Suzana Petanceska, Miguel A. Pappolla

Journal:

Neurobiology of Disease

Year:

2006

Language:

english

File:

PDF, 336 KB

english, 2006

34

Indole-3-propionate: a potent hydroxyl radical scavenger in rat brain

Burkhard Poeggeler, Miguel A. Pappolla, Rüdiger Hardeland, Arash Rassoulpour, Paul S. Hodgkins, Paolo Guidetti, Robert Schwarcz

Journal:

Year:

1999

Language:

english

File:

PDF, 106 KB

english, 1999

35

Catecholamines inhibit lipid peroxidation in young, aged, and Alzheimer’s disease brain

Anne C Andorn, Miguel A Pappolla

Journal:

Free Radical Biology and Medicine

Year:

2001

Language:

english

File:

PDF, 143 KB

english, 2001

36

Cholesterol, oxidative stress, and Alzheimer’s disease: expanding the horizons of pathogenesis

Miguel A Pappolla, Mark A Smith, Tara Bryant-Thomas, Nicolas Bazan, Suzana Petanceska, George Perry, Leon J Thal, Mary Sano, Lorenzo M Refolo

Journal:

Free Radical Biology and Medicine

Year:

2002

Language:

english

File:

PDF, 244 KB

english, 2002

37

Amphiphilic Amide Nitrones: A New Class of Protective Agents Acting as Modifiers of Mitochondrial Metabolism

Durand, Grégory, Poeggeler, Burkhard, Ortial, Stéphanie, Polidori, Ange, Villamena, Frederick A., Böker, Jutta, Hardeland, Rüdiger, Pappolla, Miguel A., Pucci, Bernard

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 952 KB

english, 2010

38

Hypercholesterolemia Accelerates the Alzheimer's Amyloid Pathology in a Transgenic Mouse Model

Lorenzo M. Refolo, Miguel A. Pappolla, Brian Malester, John LaFrancois, Tara Bryant-Thomas, Rong Wang, G.Stephen Tint, Kumar Sambamurti, Karen Duff

Journal:

Neurobiology of Disease

Year:

2000

Language:

english

File:

PDF, 166 KB

english, 2000

39

A Cholesterol-Lowering Drug Reduces β-Amyloid Pathology in a Transgenic Mouse Model of Alzheimer's Disease

L.M. Refolo, M.A. Pappolla, J. LaFrancois, B. Malester, S.D. Schmidt, T. Thomas-Bryant, G.S. Tint, R. Wang, M. Mercken, S.S. Petanceska, K.E. Duff

Journal:

Neurobiology of Disease

Year:

2001

Language:

english

File:

PDF, 192 KB

english, 2001

40

Hypercholesterolemia Accelerates the Alzheimer's Amyloid Pathology in a Transgenic Mouse Model: Volume 7, Number 4 (2000), pages 321–331

Lorenzo M. Refolo, Miguel A. Pappolla, Brian Malester, John LaFrancois, Tara Bryant-Thomas, Rong Wang, G.Stephen Tint, Kumar Sambamurti, Karen Duff

Journal:

Neurobiology of Disease

Year:

2000

Language:

english

File:

PDF, 19 KB

english, 2000

41

Carbon disulfide axonopathy. Another experimental model characterized by acceleration of neurofilament transport and distinct changes of axonal size

Miguel Pappolla, Roxanne Penton, Harold S. Weiss, Carl H. Miller Jr., Zarife Sahenk, Lucila Autilio-Gambetti, Pierluigi Gambetti

Journal:

Year:

1987

Language:

english

File:

PDF, 1.46 MB

english, 1987

42

Heat-shock induces abnormalities in the cellular distribution of amyloid precursor protein (APP) and APP fusion proteins

M.A. Pappolla, K. Sambamurti, S. Efthimiopoulos, L. Refolo, R.A. Omar, N.K. Robakis

Journal:

Neuroscience Letters

Year:

1995

Language:

english

File:

PDF, 721 KB

english, 1995

43

Luteinizing hormone modulates cognition and amyloid-β deposition in Alzheimer APP transgenic mice

Gemma Casadesus, Kate M. Webber, Craig S. Atwood, Miguel A. Pappolla, George Perry, Richard L. Bowen, Mark A. Smith

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2006

Language:

english

File:

PDF, 390 KB

english, 2006

44

Melatonin reverses the pro-fibrillogenic activity of apolipoprotein E.

Miguel A. Pappolla, Burkhard Poeggeler, J.-Y. Chyan, Tara Bryant-Thomas, Leticia Miravalle

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 183 KB

english, 2000

45

α-spectrins are major ubiquitinated proteins in rat hippocampal neurons and components of ubiquitinated inclusions in neurodegenerative disorders

José Sangerman, Alison Killilea, Robert Chronister, Miguel Pappolla, Steven R Goodman

Journal:

Brain Research Bulletin

Year:

2001

Language:

english

File:

PDF, 404 KB

english, 2001

46

O1-01-08: Cognitive impairment in heterozygous familial hypercholesterolemia

Miguel A. Pappolla, Emilio Ros, Kumar Sambamurti, Miguel Pocovi, Joyce Nicholas, Pedro Mata, Rodrigo Alonso, David Bachman, Felix Cruz-Sanchez, Jaume Benavent, Sebastian Capurro, Daniel Zambon

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 51 KB

english, 2008

47

589 Melatonin prevents oxidative damage and heat-shock protein induction in cultured cells exposed to the Alzheimer's amyloid beta protein (Aβ)

M. Pappolla, M. Sos, R. Reiter, K. Sambamurti, R. Omar, N. Robakis, S. Efthimiopoulos

Journal:

Neurobiology of Aging

Year:

1996

Language:

english

File:

PDF, 288 KB

english, 1996

48

Concurrent neuroborreliosis and alzheimer's disease: Analysis of the evidence

M.A. Pappolla, R. Omar, B. Saran, A. Andorn, M. Suarez, C. Pavia, A. Weinstein, D. Shank, K. Davis, W. Burgdorfer

Journal:

Human Pathology

Year:

1989

Language:

english

File:

PDF, 1.24 MB

english, 1989

49

Oral administration of human or murine interferon alpha suppresses relapses and modifies adoptive transfer in experimental autoimmune encephalomyelitis

Staley A. Brod, Mohammed Khan, Ronald H. Kerman, Miguel Pappolla

Journal:

Journal of Neuroimmunology

Year:

1995

Language:

english

File:

PDF, 845 KB

english, 1995

50

Complement depletion affects demyelination and inflammation in experimental allergic neuritis

Francine J. Vriesendorp, Robyn E. Flynn, Miguel A. Pappolla, Carol L. Koski

Journal:

Journal of Neuroimmunology

Year:

1995

Language:

english

File:

PDF, 2.42 MB

english, 1995

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